Fantasy Football Rankings - Week 4, 2025

Fantasy Football Rankings for Week 4 are likely to look very different between most Fantasy Football sites. Many analysts know not to overreact to what we saw in each of the first few weeks, but we definitely need to use some of the information to stay Bayesian and adjust or prior predictions. There is tremendous variance in football every week, we just don’t have enough relevant, applicable data to go from yet, but we are getting closer each week.

Terry McLaurin first 4 games of 2024:

Week 1 - 2 receptions, 4 targets, 17 yards, 0 TD

Week 1 - 6 receptions, 8 targets, 22 yards, 0 TD

Week 1 - 4 receptions, 6 targets, 100 yards, 1 TD

Week 1 - 7 receptions, 10 targets, 52 yards, 1 TD

Finished 2024 as the WR6 in half-ppr scoring

The first couple of weeks we tend to confuse outlier weeks as predictive indicators.

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Week 4 Schedule

Thursday, September 25, 2025

MATCHUP TIME TV ODDS

Seattle   @  Arizona 8:15 PM Prime Video Line: SEA -1.5 O/U: 43.5

Sunday, September 28, 2025

MATCHUP TIME TV ODDS

Minnesota   @  Pittsburgh 9:30 AM NFL Net Line: MIN -2.5 O/U: 41.5

Washington @  Atlanta 1:00 PM CBS Line: WSH -1.5 O/U: 45.5

New Orleans @  Buffalo 1:00 PM CBS Line: BUF -15.5 O/U: 47.5

Cleveland   @  Detroit 1:00 PM FOX Line: DET -9.5 O/U: 44.5

Carolina   @  New England 1:00 PM FOX Line: NE -5.5 O/U: 42.5

Los Angeles  @  New York 1:00 PM CBS Line: LAC -6.5 O/U: 43.5

Philadelphia  @  Tampa Bay 1:00 PM FOX Line: PHI -3.5 O/U: 43.5

Tennessee   @  Houston 1:00 PM CBS Line: HOU -7.5 O/U: 38.5

Indianapolis  @  Los Angeles 4:05 PM FOX Line: LAR -3.5 O/U: 49.5

Jacksonville  @  San Francisco 4:05 PM FOX Line: SF -3.5 O/U: 46.5

Baltimore   @  Kansas City 4:25 PM CBS Line: BAL -2.5 O/U: 48.5

Chicago   @  Las Vegas 4:25 PM CBS Line: LV -1.5 O/U: 47.5

Green Bay   @  Dallas 8:20 PM NBC Line: GB -6.5 O/U: 47.5

Monday, September 29, 2025

MATCHUP TIME TV ODDS

New York   @  Miami 7:15 PM ESPN Line: MIA -2.5 O/U: 44.5

Cincinnati   @  Denver 8:15 PM ABC Line: DEN -7.5 O/U: 44.5

Week 4 Must Starts

Fantasy Football Weekly Rankings

When examining these fantasy football weekly rankings, take into consideration that I am really only looking at positional ranks, not flex or overall rankings. When it comes to who you start in the flex a lot will depend on your specific league rules and roster construction. If players are ranked within 3 spots of each other the difference between them is negligible, they are expected to score the same amount of points, in those cases go with your gut, flip a coin, or join our Discord Channel.

Quarterback

Top 12 QB - Week 4 (pictures not always updated, check rankings)

Running Back

Top 12 RB - Week 4 (pictures not always updated, check rankings)

The Process

My usual process is to only take data from the previous six weeks, I truly believe anything older than that holds little relevance unless there is a player returning from injury or some reason to discount the newer information. In Week 2 we have very little information we can be confident in. The last six weeks of the previous season can give some indication, and the preseason could provide a glimpse of what’s to come or it could be a mirage.

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Wide Receiver

Top 12 WR - Week 3 (pictures not always updated, check rankings)

Tight End

Top 12 TE - Week 4 (pictures not always updated, check rankings)

Kicker

Top 12 K - Week 4 (pictures not always updated, check rankings)

Defense/Special Teams

(See rankings below for updates)

News or Hype?

Week 4 rankings are still fairly narrative based, and I will try to include that information as the week progresses. I think the best way to start our Week 4 approach is to look at implied team totals based on Vegas odds and adjust from there. We need to pay attention to DFS articles and individual player prop-bets (over/under) to get a good idea of how to project median outcomes.